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PhD Studentship: Investigation into the cytotoxic properties of extract of the plant fagonia cretica in drug-resistant cancer cells

Life and Health Sciences - Studentships

Contract Type:  Fixed Term
Basis:  Full Time
Closing Date:  23.59 hours BST on Thursday 31 August 2017
Reference:  R170368

Main Supervisor: Dr James Brown; Associate Supervisors: Dr Alice Rothnie and Professor Amtul Carmichael (Visiting Professor)

Applications are requested from highly motivated individuals for a PhD studentship that will continue previously published work in our group on the cytoxic effects of an aqueous extract of fagonia cretica in breast cancer cells.

The study will involve production of aqueous extract from fagonia cretica and subsequent analysis of its effects in drug-resistant breast cancer cells. Further work in other hormone sensitive cancers will also likely follow from this, as will analysis of the extract for candidate compounds. The study will involve extensive laboratory experimentation, especially in the areas of Cell Culture, Cell Viability and Apoptosis Analysis, qPCR, Western Blotting, Cell Migration Assays and HLPC.

The successful candidate will work within the Cell & Tissue Biomedical Research Group within the School of Life and Health Sciences at Aston University. The exceptional quality of research in the School of Life and Health sciences has been confirmed in the latest REF results - Aston University was ranked 5th out of 94 UK Higher Education Institutions for research in Allied Health Professions (REF 2014) and was ranked 1st for research environment. Additional information about research in the School can be found at http://www.aston.ac.uk/lhs/research/.

Financial Support:

The studentship is open to Home/EU students only and comprises of the current RCUK tax-free stipend of £14,553 p.a. and payment of Home/EU tuition fees only. The studentship is available for three years, subject to satisfactory progress review at the end of the first year with an anticipated registration date of 1st October 2017.

Application Requirements:

  • Eligible Applicants should hold at least a Bachelor (Hons.) Degree of either 1st Class/ 2.1 or MSc in Biology, Biomedical Sciences or a related area..

  • EU Applicants will need to demonstrate adequate proficiency in English Language skills, with a minimum overall score of 93 (Internet Based) (with a minimum score in each section of: R: 18, W: 23, L: 19 and S: 19) in TOEFL or IELTS with minimum marks of 6.0 in each section and an overall band of 6.5.

  • Informal enquiries should be addressed to Dr James Brown (E-mail: j.e.p.brown@aston.ac.uk; Telephone: +44 (0) 121 204 5039).

  • To apply please complete the on-line application form at http://www1.aston.ac.uk/lhs/research/postgraduate-research/apply/, choosing ‘Research Full-Time Biomedical Sciences September 2017’, quoting the Reference: ‘PhD_Oct 2017_Brown’ on your application..

  • The Closing Date for All Applications is: Thursday, 31st August 2017. 

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Further particulars and application forms are available in alternative formats on request i.e. large print, Braille, tape or CD Rom.

If you have any questions, please do not hesitate to contact HR via recruitment@aston.ac.uk

 

Aston University is an equal opportunities employer and welcomes applications from all sections of the community.

 


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