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Postdoctoral Research Associate in Molecular Biotechnology of Magnetotactic Bacteria

EBRI

Location:  Aston University Main Campus
Salary:  £33,797 to £35,845 per annum
Grade:  Grade 08
Contract Type:  Fixed Term (36 months)
Basis:  Full Time
Closing Date:  23.59 hours BST on Thursday 03 June 2021
Interview Date:  To be confirmed
Reference:  R210136
Release Date:  Saturday 01 May 2021

Applicants are invited to apply for a Postdoctoral Research Associate (PDRA) position to join our BBSRC-funded project on determining the molecular and metabolic mechanisms to enhance magnetosome biomanufacturing in magnetotactic bacteria.

Magnetosomes of magnetotactic bacteria (MTB) are magnetic nanomaterials with exceptional properties such as; narrow size distribution, ferrimagnetic behaviour, allowing for one-step functionalisation and are coated by an organic layer that prevents self-aggregation, which makes them extremely attractive for many nanobiotechnology and nanomedicine sectors. However, their real world application is hindered by the poor availability, due to the difficulty of growing MTB to high cell densities. To address this challenge, this project aims to investigate the mechanisms that limit productivity of both, biomass and magnetosomes, by understanding the metabolomics and transcriptomics of the MTB model Magnetospirillum gryphiswaldense (Mgryph), along with elucidating the dynamics in which iron is taken up and turned into magnetosomes. This information will be used to engineer the metabolism of Mgryph using genetic engineering tools and develop improved magnetosome bioprocessing methods.

You will have a PhD or equivalent in a relevant discipline and good knowledge and experience in microbiology, molecular biology, microbial metabolism and bioprocessing, as evidenced by your PhD thesis and/or authored papers in peer-reviewed journals. 

Further details:    Job Details    
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Further particulars and application forms are available in alternative formats on request i.e. large print, Braille, tape or CD Rom.

If you have any questions, please do not hesitate to contact HR via recruitment@aston.ac.uk

Aston University is an equal opportunities employer and welcomes applications from all sections of the community.



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